Scientific Research


 *All testing done by third-party research teams*


BIOFILAM was created and produced in Russia (VLADIVOSTOK) in the early 1990′s. It underwent rigorous research for more than five years. The main research was carried out in Russia by:

  • The State National Research Center for Preventive Medicine, 1991
  • The State Institute of Immunology, 1991
  • The State Biophysical Institute, 1994
  • The State Technical Medical Center, 1994
  • The Central Cardiovascular Hospital, 1997

The Center for Preventive Medicine had 332 subjects in their study. For six months, 158 of the 332 subjects took BIOFILAM every day. After this time, those who had taken BIOFILAM had:

  • Significant shrinking of the lymph glands which had been enlarged
  • Improved digestive systems
  • Decrease in the incidence of bronchitis by 29.5%
  • No side effects

The Institute of Immunology carried out research on volunteers from the Chernobyl region, who were exposed to radiation and heavy metal poisoning. The results of this research showed:

  • BIOFILAM is safe to use; is nontoxic and nonallergenic
  • BIOFILAM is very effective in preventing the absorption of and promoting the excretion of radioactive elements (e.g. strontium and radioactive iodine)

Some volunteers began growing back their hair which had fallen out due to exposure to radioactive elements.
Results of the research at Biophysical Institute are:

  • BIOFILAM is effective in preventing the absorption of and in promoting the excretion of radioactive elements (e.g. strontium, cesium, and radioactive iodine)
  • BIOFILAM works to protect the thyroid glands by decreasing the accumulation of radioactive iodine. As a result of this research, BIOFILAM was recommended both as a healing and preventive food supplement.

State Technical Medical Center concluded upon completion of their research that BIOFILAM is:

  • A safe food supplement
  • Recommended to increase lipid metabolism
  • Recommended to improve the function of the immune system
  • BIOFILAM is safe to use and has no harmful effects on any bodily functions or organs

At the Cardiovascular Center at the Sakhalin Hospital, patients were given up to ten grams of BIOFILAM every day for three months. The results showed:

  • Decrease of cholesterol by 26.5%
  • Decrease of B-lipoproteins by 25.1%
  • Decrease of triglycerides by 32.1%

No negative reactions were found in the kidneys, the liver and other organs. No side effects were found.

As a result of scrupulous scientific and clinical examination BIOFILAM was officially recognized as a leading prophylactic nutritional product by government of Russia. On November 12, 1997 our product was given State Certificate of Recommendation, approved by Ministry of Health. Following is the original content of that document:

ANALYTICAL REPORT on the medical-ecological examination of BIOFILAM preparation, submitted by Pacific Biotechnologies Inc.

BIOFILAM preparation, produced by Pacific Biotechnologies Co. Ltd, has been submitted for the medical-ecological examination. The examination has been conducted in accordance with “Regulations for medical-ecological examinations of preventive substances, intended for use in ecologically adverse territories” (approved by the Chairman of the Inter Departmental Scientific Council No. 50 at the Russian Academy of Medical Sciences and the Ministry of Health of the Russian Federation) by the medical-ecological research laboratory at the General Research Center of preventive medicine, Ministry of Health of the Russian Federation (Professor Y. I. Prokopenko – Director, I. N. Ilchenko – Chief Executive, V. P. Iliin – Executive Officer, A. L. Aleksandri – Executive Officer).

The goal of the medical-ecological examination of BIOFILAM preparation is to determine its potential antitoxic properties and give recommendations on its use in relation to the level of environmental pollution and the state of health.

The following List of documents has been submitted for the medical-ecological examination:

  • Application for conducting the medical-ecological examination
  • Hygienic Certificate
  • Raw material information, technology of production
  • Qualitative and quantitative structure of the preparation
  • Clinical and public tests data; experimental research data
  • Studies of the general toxic properties data

The above list of submitted documents meets the requirements of “Regulations for medical-ecological examinations of preventive substances, intended for use in ecologically adverse territories”. 


Definition of the preparation:

BIOFILAM (capsules, powders) is a natural vegetative product, made of brown seaweeds related to the genera of Alaria, Laminaria, Sargassum, Artrotamnus, Costaria and grown in the coastal seas of Sakhalin and the Kuril Islands. Capsules and powders of BIOFILAM are a balanced complex of bioactive components of the seaweeds. The main active component is the polysaccharides that are found in the preparation in significant quantities, namely, sodium alginates, fucoidan, seaweed fiber, soluble polysaccharides (bound forms of fucose, mannose, glucose, galactose, mannit). Mineral substances are found in the preparation in the bound form of inorganic salts. The most important among them are iodine, sodium, potassium, calcium, magnesium, ferrous and a range of microelements. Vitamin content in the preparation is not significant. Vitamins are represented by Vitamins A, B, C.

There are some other bioactive substances in the preparation, such as: proteins, neutral sugars, insignificant content of lipids.

The technology of producing BIOFILAM is original (patented). It allows preserving high biological activity of the separate components. As for the alginic acid – it suggests enrichment of the final product.

Quantitative estimation of ingredients found in the preparation.

Quantitative estimation of ingredients found in the preparation was conducted in accordance with the rate of daily requirement of the main active components for the ecologically normal areas and ecologically stressed.

Estimation has been made at a rate of the recommended daily dosage 5g/ day for the adults and 1.25g/ day for children.


BIOFILAM Ingredients:

Amount of substance in a daily dosage g/ mg

(% – compensation of a daily requirement)


Polysaccharides Adults Children
Alginic acid 0,68 (11,3 - 17,0) 2,7 (45,0)
Fucoidan 0,05 (-) (-)
Seaweed Fiber 0,42 (-) (-)
TOTAL: 1,15 (6, 7-9, 5) 4,57 (19,9)
Vitamins, mg (%)
A 0,01 (1, 4) 0,05 (10, 0)
B1 0,002 (0) 0,009 (0, 6)
B2 0,005 (0, 5) 0,02 (1, 2)
C 0,16 (0) 0,64 (1, 1)
Minerals, mg (%)
Na 32,3 (-) 129,0 (-)
K 55,0 (-) 220,0 (3,8)
Ca 30,1 (3,4) 120,2 (10,0)
Mg 20,7 (17,3) 82,6 (23,6)
Fe 0,77 (7,7) 3, 1 (31,0)
J 0,31 (200-300) 1, 23 (600)
Zn 0,09 (0,9) 0,35 (2,3)
Mn 0,03 (2,0) 0,11 (5,5)
Cu 0,01 (1,0) 0,05 (3,3)


The above analysis showed that active ingredients contained in BIOFILAM (represented by the polysaccharides and comprising 91% of the dry weight) cover the daily requirements for food fibers up to 5.7% – 9.5% for children and up to 19.9% for adults. Given that alginic acid, by its chemical structure and main biological properties, is close to those of pectins, the conducted analysis also gives some insight to the ratio of daily pectin requirement: 11% – 17% for children and 45% for adults.

Vitamin content in BIOFILAM is insignificant, except for Vitamin A for adults (compensates for up to 10% of the daily requirement).

As far as minerals go, BIOFILAM is rich in organic iodine, which exceeds the daily preventive dose for children 2-3 times and 6 times for adults. Scientific studies have shown that organic iodine, even in larger quantities, does not result in the oversaturation of the body. BIOFILAM contains quite a big quantity of magnesium and iron, and some calcium.


Mechanism of antitoxic activity for the main components of BIOFILAM:

The key mechanism of antitoxic activity for BIOFILAM is its adsorbent property, which puts BIOFILAM in the class of adsorbents according to the classification of antitoxic materials. Pectin containing elements, which the alginic acid in BIOFILAM is tightly related with, show high antidotal activity towards radiochemicals (Strontium, Cesium, Iodine) and heavy metals, such as: Mercury, Plumbum, Cadmium and Copper.

It’s important to note, that due to the original technology of producing BIOFILAM, the content of alginates in the final product is very high, between 30-60%, as compared to similar products made by traditional technologies, between 18-40%. The principal activity of alginates is to bond the toxic elements that may come along with food in the GI tract and then remove them through the tract.

The seaweed fibers, that are found in BIOFILAM, stimulate GI motility, increases value of many foodstuffs, improve metabolism, relieve the body of the excessive cholesterol and products of its dissolution, etc. BIOFILAM provides a normalization of the lipid exchange.

Since the intracellular and somatic polysaccharides are the structural materials and energy of cells and there are a significant amount of polysaccharides in BIOFILAM (54% – 96%) it is implied that the use of BIOFILAM as a fighting agent against immunosuppressants can protect and stimulant the immune system.

In addition there is a significant amount of organic Iodine in BIOFILAM. The Iodine is known to improve the function of the thyroid glands for individuals that are exposed to free radicals and environmental pollutants. BIOFILAM lowers absorption of the radioactive Iodine by the thyroid glands by blocking hormonogenesis of the gland, restricting accumulation of the radioactive Iodine. Apart from that, Iodine blocks atherogenic process.

Organic Magnesium and Iron are also well represented in BIOFILAM (they compensate for up to 10-30% of the daily requirement). A great many man-made pollutants and radiochemicals have a negative effect on the synthesis of heme and depress the synthesis of cytochrome oxidase. The significance of biologically digestible forms of iron increases a lot in such conditions. Biologically active Magnesium takes part in the synthesis of phosphoproteins that build quite a large part of the central nervous system. In cases of neurotropic impact of the ecotoxins on the body by the salt of free radicals, BIOFILAM may prove an efficient remedy on account of its adsorbent properties and Magnesium content.


Clinical and public tests:

Clinical test were conducted in areas with an increased level of radioactive pollution (town of Novozybkov: Cs137 – 18.1 Ci/ m2). Research work was performed by the Institute of Immunology officers. Positive effects were noted in test subjects when BIOFILAM was taken at 3.0 g/ day in the course of a month.

Public tests were conducted by the officers of the General Research Center of the Preventive Medicine, Ministry of Health, Russian Federation in the town of Klintsy with the average registered radioactive pollution level of Cs137 – 5-10 Ci/ m2 among children aged 3 – 7. BIOFILAM was prescribed over a 4 month period and the test subjects showed a reduction in the number of acute respiratory diseases, improvement in the state of pharyngonasal cavity and the lymph nodes, improvments in skin, nails, hair, mucous coat and gums were also reported.

Clinical tests of BIOFILAM were also conducted on a group of cardiac patients (ischemic heart disease, diabetes, hyper high blood pressure) at the Regional Hospital of Yuzhno-Sakhalinsk. BIOFILAM was prescribed at a daily dose of 10g over a duration of 2 months. Test results noted an increased efficiency and normalization lipid exchange (a decrease in general Cholesterol level) with the patients who suffered from general high cholesterol.

The Institute of Biophysics conducted research studies of the efficiency of BIOFILAM in blocking and reducing the absorption of radioactive Strontium, Cesium, Iodine in the GI tract.

Tests proved that the use of BIOFILAM could help reduce the amount Sr90 (Stronium) in bone tissue by up to 30%, and the amount of J131(radioactive iodine) in a thyroid gland by up 72%. Testing showed the most effective of the brown seaweed species in adsorption of radioactive Sr and J proved to be the Laminaria Japonica species.

Another research study, conducted by the Vladivostok Medical Institute showed a positive effect of BIOFILAM on lipid exchange normalization (decrease in Cholesterol), glycolysis, muscle performance and general boosts in immunity. Allergenic properties of BIOFILAM were also studied by conducting indirect degranulation of fat cells in test subjects. The results showed that BIOFILAM had no allergenic properties.


Toxicity of BIOFILAM:

Techno-Medical Center in Vladivostok assessed a general toxic activity of BIOFILAM in the process of a subacute experiment. Studies showed no toxic effects in test subjects from consuming BIOFILAM over a course of 3 months.



The detailed analysis of all materials, presented for the medical-ecological examination, makes it possible to conclude, that BIOFILAM is a highly efficiency supplement for use in detoxifying the human body of free radicals and toxic pollutants, in addition to general health benefits.

Judging by main active ingredients, BIOFILAM is classified as an “Adsorbent” of antitoxic materials; meaning that, in general, it helps to prevent toxic pollutants from absorbing into the body while the body is exposed to environmental pollution. Or it can help to detoxify or remove such toxins after exposure by literally sucking the toxins out or unabsorbing them (adsorb) and flushing them out of the system. BIOFILAM has distinct adsorption properties, lipotropic and immunogenic effects.

In summary, clinical, public and experimental research data show that BIOFILAM, can assist the general population by effectively removing radioactive Iodine, Strontium, Mercury and other free radicals from the body. BIOFILAM is recommended for use of those who are living in areas that are exposed to free radicals and toxins. 

BIOFILAM is also recommended to those who are at risk or have been affected by other ecological toxins with immunosuppressant properties (inorganic, organic compound, etc.)

BIOFILAM is recommended for those who suffer from any variety of Cardiovascular issues.

In order to get an antitoxic effect, BIOFILAM is recommended for use in the following dosages: 1.25 g/ day for children, 5 g/ day for adults. Minimum recommended duration of time is a course of 2 months.



The report was made by:

PhD. I. N. Ilchenko (Vladivostok, Russia)



**The Food and Drug Administration has not evaluated these statements.
**This product is not intended to diagnose, treat, cure or prevent any disease.